Researchers have discovered a natural compound that helps memory by boosting vitamin B6.

Researchers at the University of Würzburg in Germany have discovered a way to do this. Increase vitamin B6 By inhibiting the enzyme that breaks down B6, using a natural inhibitor. The implications of this fact may mean, in the future, Best Treatment Plans For people with debilitating mental disorders.

Vitamin B6

As can be deduced from its name. Vitamin B6 is part of the B vitamin group. It is important to Hormonal synthesis, hormonal regulation and glucose metabolismVitamin B6 plays a role in the synthesis of two essential “happiness hormones,” serotonin and dopamine; the former regulates mood and supports brain function, while the latter produces a reward response in the brain to external stimuli, facilitating motivation and memory.

Vitamin B6 promotes nerve health. By helping to form GABA, which protects nerve cells from overstimulation, helps reduce stress and improves concentration and memory. It also regulates homocysteine ​​levels, which May reduce the risk of cognitive declineVitamin B6 also helps convert glycogen into glucose, the brain's main energy reserve.

Results of previous and current studies

Researchers previously conducted experiments using mice as a model organism to study the effect of disabling the enzyme that breaks down vitamin B6, pyridoxal phosphatase. The researchers observed that Improve memory retention and spatial learning.

In a press release from the University of Würzburg, the research team identified “a natural substance capable of inhibiting pyridoxal phosphate and thus… Delaying the breakdown of vitamin B6In fact, the working group was able to increase levels of vitamin B6 in nerve cells involved in learning and memory processes. The name of this natural substance is 7,8-dihydroxyflavone.

a 7,8-dihydroxyflavone It has been widely reported in numerous research studies as: An organic compound that can improve cognition and memory retention. In experimental models of mental illness, this substance works in a similar way to brain-derived neurotrophic factor (BDNF), which is essential for maintaining brain health, cognition, and neuroplasticity.

Now that 7,8-dihydroxyflavone has been identified as an inhibitor of pyridoxal phosphatase, new information is available about the processes behind its effectiveness. 7,8-dihydroxyflavone may affect neurotransmitter levels and function by inhibiting this enzyme, allowing for a better understanding of how it may help. Alleviate symptoms of mental illness.

News Reference:

– University of Würzburg, Vitamin B6: A New Compound That Delays Decomposition.
– Brenner, M.; et al., 7,8-Dihydroxyflavone is a direct inhibitor of human and murine pyridoxal phosphatase.. Electronic Life, 2024.