This week’s photo of a 92-year-old woman who’s been wearing sunscreen for 40 years Solar Only on your face, but not on your neck. The photo was published in October 2021 in Article – Commodity Scientific warning of skin cancer in Egypt Journal of the European Academy of Dermatology and Venereology. paying off:
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In addition to being noticeable in pictureThe article written by Christian Bosch, researcher in the Department of Dermatology at the Technical University of Munich, Germany, highlights this, by Exam On clinical examination, it was possible to ascertain the difference in skin color “with marked difference in sun damage”. However, the text does not say more about the current conditions of the elderly woman.
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With the goal of preventing skin cancer, the research paper notes, “Aging is a hidden and potent trigger for skin cancer that needs to be addressed systematically to improve prevention in the future.”
The researcher celebrated via Twitter the success of the photo last Saturday. In it, he said he was “happy to see this photo circulating! Amazing!”, emphasizing the importance of the article.
with information from g 1
Skin cancer: Brazilian research discovers how to slow the progression of melanoma
A poll published by the magazine Scientific Reports He noted that a peptide – a molecule derived from a protein – developed by Brazilian scientists was able to fight skin cancer in an animal model. Rb4 peptide becomes a promising agent for the treatment of Tumors resistance drugs.
during the Search, it was possible to observe that Rb4 causes necrosis in murine melanoma cells (from mice). It can be seen that the compound inhibits the survival of human cancer cell lines, and thus cancer cells expand.
“We are doing basic science in search of new molecules. In this study, Rb4, which is derived from apolipoprotein 2, [PLP2]showed a preference for causing a specific type of cell death, necrosis, especially in skin cancer. But it is unclear how this necrosis occurs and develops. The article gives some clues to the morphological structure and final effects of contact with the peptide,” said one of the study’s authors, Fabricio Castro Machado, to FAPESP . agency.
In animals, the substance reduced lung metastasis and slowed the growth of subcutaneous melanoma. Thus, it is possible to observe that Rb4 acts directly on the tumor, leading to the expression of two damage-associated molecular patterns, called DAMPs, which induce an immunomodulatory effect during melanoma cell death.
During the tests, the researchers found that the peptide was able to interfere with morphogenesis, reproduction, and be associated with skin cancer. Rb4 was able to block cells Tumors to multiply and form clusters.
Rb4 also reduced the number of metastatic lung nodules in the synthetic melanoma model (twin animals). When compared to the control group, the the animals Treated with Rb4 had a survival rate of over 25% in up to 10 days.
Test animals received treatment with five injections of the peptide (300 μg per animal) every two days, which delayed melanoma growth for up to 40 days.
Featured image: Journal of the European Academy of Dermatology and Venereology/K. luxury
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